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Details Motilium - Domperidone Packets of 10mg x 100 tablets Manufactured by Janssen-Cilag Pty Ltd What is it used for? Symptomatic treatment of the dyspeptic symptom complex which is often associated with delayed gastric emptying or gastro-oesophageal reflux and oesophagitis: epigastric sense of fullness, feeling of abdominal distension, upper abdominal pain, eructation, flatulence, heartburn. Treatment of nausea and vomiting of various origins including functional, organic, infectious, dietetic origin, or induced by radiotherapy, medicine therapy. How do you take it? MOTILIUM should be taken 15-30 minutes before meals and, if necessary, before retiring. Domperidone is used in Canada and other areas of the world to increase milk supply.Domperidone increases milk supply by blocking dopamine, which results in an increase in prolactin levels. It does not work in all women and would not be expected to increase milk production in a woman who already has normal (high) prolactin levels.