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Details ZESTRIL/PRINIVIL – (Lisinopril) Packets of 30 x 20 mg Tablets Manufactured by Astra Zeneca What is it? Zestril/Prinivil is used in the treatment of high blood pressure. It is effective when used alone or when combined with other high blood pressure medications. It may also be used with other medications in the treatment of heart failure, and may be given within 24 hours of a heart attack to improve chances of survival. Zestril/Prinivil is a type of drug called an ACE inhibitor. It works by reducing production of a substance that increases salt and water retention in your body. How do you take it? Zestril/Prinivil can be taken with or without food. Take it exactly as prescribed. Stopping Zestril/Prinivil suddenly could cause your blood pressure to rise. What are the side effects? More common side effects may include chest pain, cough, diarrhoea, dizziness, headache, low blood pressure. Less common or rare side effects may include abdominal pain, anemia, arm pain, arthritis, asthma, back pain, blood clots, blurred vision, breast pain, bronchitis, chills, common cold, confusion, constipation, coughing up blood, stomach cramps, decreased sex drive, dehydration, diabetes, dizziness, double vision, dry mouth, fainting, fatigue, feeling of illness, fever, fluid retention, flushing, gas, gout, hair loss, heart attack, heartburn, hepatitis, hip pain, hives, impotence, insomnia or sleeping excessively, indigestion, inflamed stomach, intolerance of light, irregular heartbeat, irritability, joint pain, kidney trouble or failure, knee pain, laryngitis, leg pain, little or no urine, lung cancer, lung inflammation, memory impairment, muscle pain or cramps, nausea, neck pain, nervousness, nosebleed, numbness or tingling, painful breathing, painful urination, pelvic pain, pneumonia, prickling or burning sensation, rapid or fluttery heartbeat, rash, respiratory infection, ringing in ears, shoulder pain, sinus inflammation, spasm, stroke, sweating, swelling of face or arms and legs, thigh pain, tremor, urinary tract infection, vertigo, virus infection, vomiting, weakness, weight loss or gain, wheezing, yellow eyes and skin. What precautions should be taken? If you have high blood pressure, you must take Zestril/Prinivil regularly for it to be effective. Since blood pressure declines gradually, it may be several weeks before you get the full benefit of Zestril/Prinivil; and you must continue taking it even if you are feeling well. Zestril/Prinivil does not cure high blood pressure; it merely keeps it under control. Make sure your doctor is aware of any drug reactions you have experienced. If you are being given bee or wasp venom to guard against future reactions, you may have a severe reaction to Zestril/Prinivil. If you have congestive heart failure or other heart problems, a kidney disorder, or a connective tissue disease such as lupus, you should use this drug with caution. This drug also should be used with caution if you are on dialysis. There have been reports of extreme allergic reactions during dialysis in people taking ACE inhibitor medications such as Zestril/Prinivil. If you are taking high doses of a diuretic (water pill) and Zestril/Prinivil, you may develop excessively low blood pressure. Do not drive, operate dangerous machinery, or participate in any hazardous activity that requires full mental alertness until you are certain Zestril/Prinivil does not have this effect on you. Avoid salt substitutes that contain potassium. Limit your consumption of potassium-rich foods such as bananas, prunes, raisins, orange juice, and whole and skim milk. Ask your doctor for advice on how much of these foods to consume.